Antidiabetic activity of alcoholic stem extract of. Coscinium fenestratum, or yellow vine as it is sometimes referred to in english, is a flowering woody climber, native to south asia and mainland southeast asia. Traditional uses of medicinal plants in polonnaruwa district in north. All structured data from the file and property namespaces is available under the creative commons cc0 license. Stem is commercially important which have multiple medicinal used and therapeutic efficacy. Collebr, an important ayurvedic plant, revealed the presence of significant. Coscinium fenestratum is a common medicinal plant widely used in the indochina region, but scienti. Introduction diabetes mellitus is a syndrome of impaired carbohydrate, fat, and protein metabolism caused by either lack of insulin secretion or by decreased sensitivity of the tissues to insulin characterized by chronic hyperglycemia setter et al. Coscinium fenestratum in noninsulin dependent diabetic rats. Coscinium fenestratum considered as a critically endangered medicinal plant belongs to the family menispermaceae. Request pdf anatomy of coscinium fenestratum gaertn.
That is tree turmeric false columba tree turmeric is scientifically known as coscinium. Coscinium fenestratum protects against ethanolinduced. Indian medicinal plant, coscinium fenestratum a new ijhm. Pdf genetic structure and diversity of coscinium fenestratum. Coscinium usitatum pierre coscinium wallichianum miers coscinium wightianum miers ex diels menispermum fenestratum gaertn.
Coscinium fenestratum, menispermaceae, streptozotocinnicotinamideinduced diabetes. Menispermaceae, a medicinal plant widely used in the traditional ayurveda and siddha systems of medicine for the treatment of diabetes mellitus was evaluated in. The synthetic antioxidants have been suspected to cause or prompt negative health effects leading to extensive research on naturally occurring antioxidants especially from plant. Pdf evaluation of cytotoxic and antitumor activities of. Introduction the contamination of water and soil in farmland and surrounding environment by carbamate pesticide has been. It doesnt matter how complex they are or how many pages each pdf has, pdf2go merges them all into.
In vitro seed germination of coscinium fenestratum gaertn. Department of agriculture agricultural research service. Alcoholic stem extract of coscinium fenestratum regulates. Research article cytotoxic effect of coscinium fenestratum on human head and neck cancer cell line hn31 saranyapinpotikanond, 1 natthakarnchiranthanut, 1 pariratkhonsung, 1 andsupanimitteekachunhatean 1,2 department of pharmacology, faculty of medicine, chiang mai university, chiang mai, a iland.
It is a large, dioecious and woody climber that belongs to menispermaceae family. Coscinium fenestratum ecdysterone first reportayurvedicdaru haridra 1. This has lead to a rapid decline in the population size and has also led to local population extinction at few locations in the. Coscinium fenestratum is the source of crucial ayurvedic raw drug daruharidra dating back to several centuries. Evaluation of antioxidant properties of 20 medicinal plant. Menispermaceae are used in indian systems of medicine. Indian medicinal plant, coscinium fenestratum international. The species is seen confined to the semievergreen and wet evergreen forests.
The alkaloid berberine isolated from coscinium fenestratum. Pdf phytochemical investigation and hepatoprotective. Pharmacognostical and proximal analysis of two different. Coscinium fenestratum, daruharidra, quantification, uplc esi msms, alkaloids. It has found its way to europe as tree turmeric or false claumba. Effect of coscinium fenestratum on hepatotoxicity in rats. Pdf on jan 1, 2016, suman kashyap and others published coscinium fenestratum. The antidiabetic potential of the alcoholic stem extract of coscinium fenestratum colebr. Collebr, an important ayurvedic plant, revealed the presence of significant amounts of ecdysterone in the stem 0. In the present study, berberine content was quantified in c. Callus and suspension cell culture of the endangered medicinal plant using vermicompost extract and coelomic fluid as plant tissue culture media. The author explains in this paper that the use of coscinium fenestratum in the name of daru haridra by the keralaphysicians is justifiable basing on its literal meaning in malayalam mara mannal and the similarity in the therapeutic action to that berberis species. Studies on seed germination of coscinium fenestratum. Coscinium fenestratum in the germplasm resources information network grin, u.
The enhanced carbamate adsorption of modified bentonite. Menispermaceae is widely spread across the western ghats india and sri lanka. Usda, ars, germplasm resources information network. Research article cytotoxic effect of coscinium fenestratum. Simultaneous quantification of protoberberine and aporphine. Leaves 1518 x 15 cm, ovate, apex acuminate, base truncate, 57 ribbed, deltoid. A critically endangered medicinal plant from western ghats coscinium fenestratum is a. Menispermaceae, a medicinal plant widely used in the traditional ayurveda and siddha systems of medicine for the treatment of diabetes mellitus was evaluated in the stznicotinamide induced type 2 diabetic model. Pdf variation of berberine content in coscinium fenestratum. Coscinium fenestratum diabetic rats hypoglycaemic liver and kidney functions standardized extract corresponding author. Berberine content in coscinium fenestratum grown in sri lanka.
In the present study an attempt was made to isolate flavonoids and to evaluate. Quantification of berberine content in coscinium fenestratum methanolic. Pdf dormancy and germination of coscinium fenestratum. Dhar natural products chemistry division, regional research laboratory, canal road, jammutawi 180001, india received in revised form 7 october 1988 key word indexcoscinium. This plant is known to have hypoglycemic shirwarkar et al. This free online tool allows to combine multiple pdf or image files into a single pdf document. Antioxidant properties of coscinium fenestratum stem extracts on streptozotocin induced type 1 diabetic rats neethu p. Coscinium fenestratum, berberine, antimicrobial activity, antifungal activity, antimicrobial activity profile citation. Introduction coscinium fenestratum gaertner colebr. Alcoholic extract of the stems of coscinium fenestratum, a medicinal plant indigenous to india and sri lanka used in ayurveda and siddha medicine for treating diabetes, was studied for its carbohydrate metabolism effect and antioxidant status in streptozotocinnicotinamide induced type 2 diabetic rats. It is found in india, malaysia, vietnam, myanmar, singapore, thailand and sri lanka tushar et al. Suspension medium was developed using vermicompost extract and coelomic fluid in. Phytochemical investigation and hepatoprotective activity of coscinium fenestratum colebr.
Synonyms coscinium maingayi pierre coscinium miosepalum diels coscinium peltatum merr. The habitat for coscinium fenestratum spans south asia and parts of southeast asia, from india to indonesia. Coscinium fenestratum colebr cf menispermaceae, grows widely in the indochina region. Coscinium fenestratum seeds with 23 % initial moisture content showed 40 % germination over a period of 4 months incubation. In vitro tissue culture of hard woody, endangered, medicinal plant coscinium fenestratum is most challenging to plant tissue culturists. Minor alkaloid from coscinium fenestratum sciencedirect. The extract was filtered and the filtrate was evaporated to dryness under reduced pressure at 50 c. Proceedings of the 8h academic sessions, university of ruhuna 2010 vol. Antioxidant properties of coscinium fenestratum stem extracts. Menispermaceae is one of the most important plants used in traditional systems of medicine. Coscinium maingayi pierre coscinium miosepalum diels coscinium peltatum merrill coscinium usitatum pierre coscinium wallichianum miers coscinium wightianum miers coscinium wightianum miers ex diels menispermum fenestratum gaertn. Files are available under licenses specified on their description page. However, the former drug plant is considered as genuine and the latter as substitute.
Introduction coscinium is a dioecious woody climber from the family menispermaceae and in india it is endemic to the western ghats, especially in high rainfall wet evergreen and semi evergreen forests. See status, confidence level, source for definitions. Molecular identification and development of nuclear dna its. The dictionary of indian raw materials and industrial products. Genetic structure and diversity of coscinium fenestratum. Antioxidant properties of coscinium fenestratum stem.
Merge pdf documents or other files to one pdf file. In the present study, petiole and leaf explants of coscinium fenestratum were induced to form callus when cultured on vermicompost extract media along with coelomic fluid. Phytochemical investigation on coscinium fenestratum gaertn. Antidiabetic activity of alcoholic stem extract of coscinium. This plant has been mainly used for treating diabetes mellitus in the traditional ayurvedic and siddha systems of medicine warrier et al. The results revealed that cell morphology visualized under inverted light microscopy was. Menispermaceae, an endangered and highly commercial medicinal plant of traditional system of medicine. Department of crop science, faculty of agriculture. In vitro antigonococcal activity of coscinium fenestratum stem. Coscinium fenestratum is widely used as a medicinal plant in many asian countries.
Free web app to quickly and easily combine multiple files into one pdf online. Coscinium fenestratum belongs known herb in ayurvedic system of medicine. Menispermaceae, called hamm in thai, is a traditional medicine of the northeastern part of thailand. Conservation assessment and management plan workshop for ntfp of nbr april 2001 1 conservation assessment and management plan workshop camp for nontimber forest products of nilgiri biosphere reserve executive summary the nilgiri biosphere reserve nbr is a particularly rich area biologically of the western ghats. Stem has been used for long in south india and sri lanka as a yellow dye and bitter tonic. Berberine is the main isoquinoline alkaloid that was presented the natural organic monovalent cation in c. It is rare and critically endangered in many of its habitats. This study aimed to investigate the cytotoxic effect of a crude water extract of c. Antidiabetic activity of alcoholic stem extract of coscinium fenestratum in streptozotocinnicotinamide induced type 2 diabetic rats.
The alkaloid berberine isolated from coscinium fenestratum is an inhibitor of phytopathogenic fungi. Our pdf merger allows you to quickly combine multiple pdf files into one single pdf document, in just a few clicks. Coscinium fenestratum is a member of the family menispermaceae and the genus coscinium. Today we are going to discuss about another important herb which is effective in the immune enhancing.
Free radicals contribute to more than one hundred disorders in humans. Cytotoxic effect of coscinium fenestratum on human head. The plant has been determined to be native to sri lanka and the western ghats in india. The objective of the study is to evaluate the effect of extraction, content of elements and their correlation on proximate analysis and. Publication and information directorate, csir, new delhi, india. Botanical occurrence, traditional uses, extraction.
It is one among the families having several medicinal values from root to fruit. Callus and suspension cell culture of the endangered medicinal plant. The present investigation was aimed to study the in vitro seed germination potential of coscinium fenestratum an endangered woody climber with high medicinal value to ensure germplasm conservation and mass production of planting material to meet the unlimited demand. It can only thrive in a tropical climate and prefers mixed and dense evergreen forest, with fertile soil and high moisture.
The alkaloid berberine isolated from coscinium fenestratum is. The genus coscinium is in the family menispermaceae in the major group angiosperms flowering plants. Isolation of endophytic fungi from coscinium fenestratum gaertn. Coscinium fenestratum plant will be further studied for its contribution to pesticide adsorption material in thailand. Berberine, coelomic fluid, coscinium fenestratum, plant tissue culture media, suspension cell culture, vermico mpost extract 1. Index termsbentonite, berberine, modification, carbaryl, adsorption, coscinium fenestratum. Aug 29, 20 coscinium fenestratum is a critically endangered medicinal plant, wellknown for its bioactive isoquinoline alkaloid berberine. Akowuah, faculty of pharmaceutical sciences, ucsi university, no. Isolation of endophytic fungi from coscinium fenestratum.
The enhanced carbamate adsorption of modified bentonite with. Pdf coscinium fenestratum is a critically endangered medicinal plant, well known for its bioactive isoquinoline alkaloid berberine. In vitro antigonococcal activity of coscinium fenestratum stem extract. Menispermaceae, a critically endangered and highlytraded medicinal plant, has become very important in recent years due to its rarity and huge demand in the medicinal plant sector. Pdf antidiabetic activity of alcoholic stem extract of.
The root, root bark and stem of berberis aristata dc berberidaceae and the root, stem and stem bark of coscinium fenestratum gaertn. Coscinium fenestratum, its sequence, adulterants, dna marker, pharmacognosy, quality control introduction coscinium fenestratum gaertn. Media in category coscinium fenestratum the following 17 files are in this category, out of 17 total. Coscinium wallichianum miers coscinium wightianum miers ex diels. Uttar kannada districts, kerala thiruvananthapuram, wynaad, thrissur, idukki and palakkad and tamil nadu kanyakumari, tirunelveli and nilgiri districts up to an altitude of m msl. To evaluate the anti tumor activity of coscinium fenestratum extract under in vitro and in vivo conditions. It grows well in western ghats india and sri lanka. Cytotoxic effect of coscinium fenestratum on human head and. Coscinium is a genus of flowering plants in the family menispermaceae. Neurotoxicity of coscinium fenestratum stem, a medicinal.